Finbarr Cotter, MD, PhD from British Society of Hematology (BSH) Conferences and Barts Health NHS Trust, UK discusses some of the topics covered in the 2016 Annual Meeting of the BSH and International Society of Hematology (ISH) held in Glasgow, Scotland. These topics include chronic lymphocytic leukemia (CLL) and its associated kinase inhibitors and monoclonal antibodies, as well as use of prognostic markers and whole genome sequencing. Prof Cotter also speaks of issues arising from histiocytosis.