MPN Advances Day 2017 | Is the order of mutations leading to cancer important?

Tony Green

Cancers, such as myeloproliferative neoplasms (MPNs), evolve from repeated mutations; it is unlikely that one mutation alone causes cancer. In this interview, Tony Green, MD, PhD, of the University of Cambridge, discusses some interesting findings regarding the importance of the order of mutations that have been implicated in a cancer, such as JAK2 and TET2 in MPNs, and how the behavior of the disease and its effect on the patient can be affected by this. This video was recorded at the Myeloproliferative Neoplasms Advances Day 2017 in London, UK.

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