Sergio Giralt, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses transplant-associated thrombotic microangiopathy (TA-TMA), and the strategies to prevent and treat this transplantation complication. This interview took place at the 5th International Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) 2019, held in Berlin, Germany.