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ASH 2022 | Update on Phase I study of plamotamab in R/R NHL

Krish Patel, MD, Swedish Cancer Institute, Seattle, WA, gives an update on a Phase I trial (NCT02924402) of plamotamab in patients with relapsed/refractory (R/R) non-Hodgkin lymphoma (NHL). The study reported a manageable toxicity profile, and a benefit with plamotamab in this heavily pre-treated patient group with respect to overall response (OR) and complete response (CR) rates. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

BeiGene: Consultancy; Epizyme: Consultancy, Research Funding; Curis, Inc: Research Funding; Fate Therapeutics: Research Funding; Genetech/Roche: Consultancy, Research Funding, Speakers Bureau; Caribou Biosciences: Consultancy; Celgene: Consultancy, Research Funding, Speakers Bureau; CRISPR Therapeutics: Research Funding; ADC Therapeutics: Consultancy; Bristol Myers Squibb: Consultancy, Research Funding, Speakers Bureau; Aptevo Therapeutics: Research Funding; AstraZeneca: Consultancy, Research Funding, Speakers Bureau; MEI Pharma: Consultancy, Research Funding; Kite pharma: Consultancy, Research Funding, Speakers Bureau; Loxo Oncology: Consultancy, Research Funding; Morphosys: Consultancy; Nurix: Research Funding; Pharmacyclics/Janssen: Consultancy, Research Funding, Speakers Bureau; Sunesis Pharmaceuticals: Research Funding; TG Therapeutics: Consultancy, Speakers Bureau; Trillium Therapuetics/Pfizer: Consultancy, Research Funding; Velos Bio: Research Funding; Xencor: Consultancy, Research Funding; Abbvie: Consultancy; Adaptive Biotechnologies: Research Funding.