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ICML 2023 | Predicting response to CAR-T therapy in lymphoma: challenges and strategies

Michael Green, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the challenges in predicting patient response to CAR-T therapy, which can be dependent on a variety of factors such as the tumor microenvironment and the patient’s T-cells. Dr Green describes a metric which is currently used and highlights the need for a more holistic model. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.

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Disclosures

Research funding from Sanofi, Kite/Gilead, Abbvie and Allogene; consulting for Abbvie, Allogene and Bristol Myers Squibb; honoraria from Tessa Therapeutics, Monte Rosa Therapeutics, Daiichi Sankyo and DAVA Oncology; and stock ownership of KDAc Therapeutics