The practical takeaway is not so easy because it’s not that you can say this type of patient has this type of treatment. I think the practical takeaway is that do the risk factor assessment like TP53 and IGHV status, assess the patient’s history, his expectations also for the treatment, if it’s more important for him to have a long time without treatment, a long treatment-free survival, deep remission, or if the patient is rather interested in having fewer visits at his physician’s desk, also depending on his environment, his family...
The practical takeaway is not so easy because it’s not that you can say this type of patient has this type of treatment. I think the practical takeaway is that do the risk factor assessment like TP53 and IGHV status, assess the patient’s history, his expectations also for the treatment, if it’s more important for him to have a long time without treatment, a long treatment-free survival, deep remission, or if the patient is rather interested in having fewer visits at his physician’s desk, also depending on his environment, his family. And depending on that, you can then choose the treatment with the patient. In summary, the good news, as long as you don’t give any chemotherapy, there is not so much you can do wrong with your patients.
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