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IWWM-11 2022 | An insight into molecular clusters and tumor-immune drivers in WM

Stephen Ansell, MD, PhD, Mayo Clinic, Rochester, MN, discusses the clinical variation of molecular clusters and tumor-immune drivers in Waldenström’s macroglobulinemia (WM), highlighting findings from a study which used a multi-omics approach to characterize patients. Prof. Ansell explains how these clusters may play a role in disease progression and further comments on the role of the tumor immune microenvironment in WM. This interview took place at the 11th International Workshop on Waldenström’s Macroglobulinemia (IWWM-11), held in Madrid, Spain.

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Disclosures

Research funding from Seattle Genetics, BMS, Affimed, Regeneron, Takeda, AstraZeneca, Pfizer, ADC Therapeutics to my institution for clinical trials.