Sarah K. Tasian, MD, University of Pennsylvania School of Medicine and Abramson Cancer Center, Philadelphia, PA, outlines the use of blinatumomab and inotuzumab for the treatment of children with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). The study reported that both blinatumomab and inotuzumab can induce deep remissions in patients with R/R B-ALL and that blinatumomab can be used as an effective bridging therapy during infection. This interview took place at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021.