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SOHO 2025 | Lisaftoclax combinations in R/R myeloma and AL amyloidosis

Jack Khouri, MD, Cleveland Clinic, Cleveland, OH, discusses the safety and efficacy of the novel BCL-2 inhibitor lisaftoclax in different combinations for patients with multiple myeloma and light chain (AL) amyloidosis. The data showed that lisaftoclax was well-tolerated in both cohorts, with low-grade hematologic adverse events and no major serious adverse events. This interview took place at the 13th Annual Meeting of the Society of Hematologic Oncology (SOHO 2025) in Houston, TX.

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