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ERIC 2022 | The impact of genetic abnormalities on treatment decisions in CLL

Antonio Cuneo, MD, St. Anna University Hospital, Ferrara, Italy, discusses the importance of genomic testing prior to treatment initiation in chronic lymphocytic leukemia (CLL), highlighting the impact of TP53 mutations, 17p deletion (del 17p), and immunoglobulin gene (IgG) mutations on treatment decisions, and outlining methods used to detect these abnormalities. According to Dr Cuneo, patients who do not carry IgG mutations, or patients who carry del 17p or TP53 mutations should not be treated with chemoimmunotherapy. This interview took place at the 2022 European Research Initiative on CLL (ERIC) Meeting.

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