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EHA 2024 | The role of the immune system in the pathophysiology of MDS

Uwe Platzbecker, MD, University of Leipzig, Leipzig, Germany, discusses the immune system’s role in the pathophysiology of myelodysplastic syndromes (MDS) and its potential targeting to restore hematopoiesis. He highlights the modulation of checkpoint molecules with antibodies and the potentially curative role of CAR T-cells. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Consultancy: AbbVie, Novartis, Jazz, Bristol Myers Squibb, Servier, Janssen Biotech, Syros, Amgen, Curis, Geron, Silence Therapeutics, Takeda
Honoraria: Novartis, Jazz, Bristol Myers Squibb, Servier, Syros, Celgene, Silence Therapeutics, Takeda
Research Funding: Novartis, Roche, BeiGene, Jazz, Bristol Myers Squibb, Servier, Janssen Biotech, Syros, Merck, Fibrogen, Amgen, Curis, Geron, BMS, Silence Therapeutics, Takeda
Board of Directors/Advisory Committee: MDS Foundation, Bristol Myers Squibb
Travel Support: Bristol Myers Squibb
Medical Writing Support: Bristol Myers Squibb