Maarten Vermeer, MD, PhD, Leiden University Medical Center, Leiden, Netherlands, talks on the management of early-stage mycosis fungoides, discussing the initial use of local therapies such as steroids and radiotherapy, but outlining the need for systemic therapies where there is lymph node, organ or blood involvement. Dr Vermeer comments on the need for more efficacious systemic therapies in these instances. This interview took place at the EORTC Cutaneous Lymphoma Group 20-21 meeting in Marseille.