Kerry Rogers, MD, The Ohio State University, Columbus, OH, provides an overview of findings from a Phase Ib dose-escalation and -expansion trial (NCT03400176) of ianalumab, an anti-BAFF monoclonal antibody, and ibrutinib in patients with chronic lymphocytic leukemia (CLL). Ianalumab with ibrutinib was shown to have a good safety profile, and promising efficacy, where undetectable minimal residual disease (MRD) was reported in multiple patients. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.
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