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ASH 2023 | A research update in Richter’s transformation from ASH 2023

Tanya Siddiqi, MD, City of Hope, Duarte, CA, gives a brief update on research into Richter’s transformation (RT), a challenging complication of chronic lymphocytic leukemia (CLL). Dr Siddiqi highlights promising data from the CLL-RT1 trial (NCT04271956), showcasing the efficacy of tislelizumab, a PD1 inhibitor, combined with zanubrutinib in the treatment of RT. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Juno therapeutics, AbbVie, Kite Pharma, Celgene, BeiGene, AstraZeneca, BMS
Research Funding: Juno therapeutics, TG therapeutics, Oncternal, Pharmacyclics, LLC an AbbVie Company, Ascentage Pharma, Kite Pharma, Celgene, BeiGene, AstraZeneca
Speakers Bureau: Janssen, BeiGene, AstraZeneca, BMS
Board of Directors/Advisory Committee: AbbVie, Kite Pharma, Celgene, BeiGene, AstraZeneca, BMS