Iuliana Vaxman, MD, Mayo Clinic, Rochester, MN, discusses the role of autologous hematopoietic stem cell transplantation (autoHSCT) in immunoglobulin light-chain (AL) amyloidosis. Dr Vaxman explains that only 20% of patients with AL amyloidosis are eligible for autoHSCT and it is therefore crucial to select the right patients to undergo this treatment. However, there is currently no data outlining patient selection criteria in this setting. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.