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EBMT 2024 | The MAGIC model: a day 14 endpoint for acute GvHD clinical trials

James Ferrara, MD, DSc, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, introduces the MAGIC model, which considers clinical features and biomarkers to predict outcomes of treatment for acute graft-versus-host disease (GvHD). This model can predict outcomes at day 14 of treatment more accurately than previous models which only consider clinical features. Dr Ferrara suggests day 14 should be a new endpoint in GvHD clinical trials. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.

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Disclosures

I hold a patent for serum biomarkers of acute GVHD which is licensed and for which I receive royalties.