ASH 2022 | Long-term post hoc analysis of MURANO Trial: host immune changes following VenR treatment in CLL
Arnon Kater, MD, PhD, University of Amsterdam, Amsterdam, Netherlands, reports on a study that assessed the long-term, post-treatment immune changes observed in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) that participated in the MURANO phase III trial (NCT02005471). This analysis revealed that patients that completed the fixed-duration course of treatment with venetoclax and rituximab (VenR) demonstrated immune recovery with respect to their immunoglobulins and T-cell compartments. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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Disclosures
Abbvie, Astra Zeneca, BMS, Janssen, Roche/Genentech: Research Funding; Janssen, LAVA: Patents & Royalties: Pending; Astra Zeneca, BMS, Roche/Gennetech, Janssen, Abbvie, LAVA: Membership on an entity’s Board of Directors or advisory committees; Abbvie, Astra Zeneca, Janssen: Other: Speakers fee; Amsterdam UMC, University of Amsterdam: Current Employment
