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EHA 2024 | Comparative efficacy of teclistamab vs pom+dex in triple-class exposed R/R myeloma

Rakesh Popat, BSc, MBBS, MRCP, FRCPath, PhD, University College London Hospitals, London, UK, explains the rationale for and presents the findings of a matching-adjusted indirect comparison (MAIC) that assessed the efficacy of teclistamab versus pomalidomide (pom) plus dexamethasone (dex) for patients with triple-class exposed relapsed/refractory (R/R) multiple myeloma (MM) in England. The findings of this MAIC suggest that, in this patient population, teclistamab elicits superior response rates and a longer time to next treatment (TTNT). This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

GSK: Consultancy, Honoraria, Research Funding; Janssen: Honoraria; BMS: Honoraria; AbbVie: Honoraria; Roche: Honoraria; University College London Hospitals NHS Foundation Trus: Current Employment. Gironella: Janssen: Consultancy, Honoraria; GSK: Consultancy.