Borja Puertas, MD, University Hospital of Salamanca, Salamanca, Spain, discusses the impact of measurable residual disease (MRD) in apheresis product (aMRD) assessed by multiparametric flow cytometry (MFC) in transplant-eligible patients with multiple myeloma (MM). A study involving over 400 patients undergoing autologous stem cell transplantation (autoSCT) highlighted that MRD positivity in the apheresis product correlates with shorter progression-free survival (PFS) and poorer treatment responses. Dr Puertas suggests that MRD positivity may also help identify patients with functional high-risk disease. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.
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