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IMS 2024 | The impact of MRD in apheresis product in patients with myeloma undergoing autoSCT

Borja Puertas, MD, University Hospital of Salamanca, Salamanca, Spain, discusses the impact of measurable residual disease (MRD) in apheresis product (aMRD) assessed by multiparametric flow cytometry (MFC) in transplant-eligible patients with multiple myeloma (MM). A study involving over 400 patients undergoing autologous stem cell transplantation (autoSCT) highlighted that MRD positivity in the apheresis product correlates with shorter progression-free survival (PFS) and poorer treatment responses. Dr Puertas suggests that MRD positivity may also help identify patients with functional high-risk disease. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.

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