ASH 2023 | Copanlisib, rituximab, & bendamustine in transplant-ineligible R/R DLBCL
Umberto Vitolo, MD, Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy, outlines the findings of the Phase II FIL Copa-RB trial (NCT02391116) which aimed to investigate the combination therapy of copanlisib, rituximab, and bendamustine for the treatment of transplant-ineligible relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). Unfortunately, due to an unfavorable safety profile and recruitment challenges due to the COVID-19 pandemic, this study was terminated prematurely, and the development of this combination in this patient population is not continuing. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Lecture Fees: Servier, Roche, Janssen, Incyte, AbbVie; Membership on an entity’s Board of Directors or advisory committees: Novartis, Gilead, Genmab, Bayer.
