Arnon Kater, MD, PhD, University of Amsterdam, Amsterdam, The Netherlands, shares his highlights from ASH 2020. Prof. Kater discusses updates from the CLL14 trial (NCT02242942) comparing obinutuzumab plus venetoclax with obinutuzumab plus chlorambucil in patients with chronic lymphocytic leukemia (CLL). He also outlines advances in chimeric antigen T-cell receptor (CAR-T) therapy and with the BTK inhibitor LOXO-305. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.