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EBMT 2024 | Comparing haploSCT to other donor types in lymphoma treatment

Ali Bazarbachi, MD, PhD, American University of Beirut, Beirut, Lebanon, discusses the use of haploidentical stem cell transplantation (haploSCT) in treating non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). This approach allows all transplant-eligible patients to receive treatment, with post-transplant cyclophosphamide (PTCy) as graft-versus-host disease (GvHD) prophylaxis significantly improving outcomes. While haploSCT demonstrates promising results compared to cord blood and matched unrelated donors, in the context of PTCy-based prophylaxis, HLA-matched sibling donors have more favorable outcomes. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.

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