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ASH 2022 | Azacitidine and venetoclax +/- gemtuzumab ozogamicin in pediatric patients with R/R acute leukemias

Sarah Tasian, MD, Children’s Hospital of Philadelphia, Philadelphia, PA, discusses a retrospective cohort analysis evaluating the combination of azacitidine and venetoclax +/- gemtuzumab ozogamicin for the treatment of pediatric patients with relapsed/refractory (R/R) acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Dr Tasian highlights the complete remission (CR) rates observed in patients and further comments on the promise of this combination regimen. This interview took place at the 64th ASH Annual Meeting and Exposition congress held in New Orleans, LA.

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Aleta Biotherapeutics: Consultancy; Beam Therapeutics: Research Funding; bluebird bio: Consultancy; Syndax Pharmaceuticals: Consultancy; Kura Oncology: Consultancy, Research Funding; GSK: Consultancy; Incyte Corporation: Research Funding.

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