Nirali Shah, MD, National Cancer Institute, National Institutes of Health, Bethesda, MD, talks on the management of the infectious complications of chimeric antigen receptor T-cell (CAR-T) therapies targeting different antigens, commenting on implications for clinical practice. This interview took place at the 6th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM), which took place virtually.