Constantine Tam, MBBS (Hons), MD, FRACP, FRCPA, Alfred Hospital and Monash University, Melbourne, Australia, discusses the updated results of the ALPINE trial (NCT03734016), which compared the BTK inhibitors ibrutinib and zanubrutinib in patients with chronic lymphocytic leukemia (CLL). The findings of this study have been somewhat controversial, as zanubrutinib has shown prolonged progression-free survival (PFS) and superior efficacy to ibrutinib, including in high-risk patients with 17p deletion. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.