Kirsten Fischer of the University of Cologne, Cologne, Germany, discusses data on a new fixed-duration targeted therapy with venetoclax plus obinutuzumab in previously untreated patients with chronic lymphocytic leukemia (CLL) and coexisting comorbidities. Dr Fischer presents the results of the CLL14 study (NCT02242942), with a particular emphasis on efficacy and MRD data. This press briefing was recorded at the 24th Congress of the European Hematology Association (EHA) 2019, held in Amsterdam, Netherlands.