Michael Bishop, MD, University of Chicago Medical Center, Chicago, IL, discusses the CAR-T research he is most excited about, where the field is likely to move, and the prospect of CAR-T becoming a globally used therapy, replacing more conventional therapies. This interview took place at the 5th International Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) 2019, held in Berlin, Germany.