Rory Shallis, MD, Yale Cancer Center, New Haven, CT, introduces the ongoing Phase II VICTORY MDS/MPN trial (NCT05600894), evaluating the efficacy of ASTX727 (oral decitabine-cedazuridine) monotherapy and ASTX727 with venetoclax in patients with newly diagnosed myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN). The trial focuses on establishing complete response (CR) rates, with secondary endpoints including overall survival (OS) and measurable residual disease (MRD) outcomes. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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