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ASH 2022 | Validation of the IPSS-M risk stratification system in MDS

Rami Komrokji, MD, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, addresses the novel Molecular International Prognostic Scoring System (IPSS-M), and describes a study validating its use in the risk stratification of patients with myelodysplastic syndromes (MDS). Patients previously classified using the Revised International Prognostic Scoring System (IPSS-R) were re-classified using the IPSS-M, which gave accurate predictions of leukemia-free and overall survival (OS). Dr Komrokji also highlights the need to address how reclassification with the IPSS-M may impact treatment strategies. This interview took place at the 64th ASH Annual Meeting and Exposition congress held in New Orleans, LA.

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Disclosures

Jazz: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; PharmaEssentia: Honoraria, Other, Speakers Bureau; CTI biopharma: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; Servio: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; BMS: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Novartis: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Abbvie: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Geron: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Taiho: Honoraria, Membership on an entity’s Board of Directors or advisory committees.