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EBMT 2026 | Assessing frailty to improve stem cell transplant outcomes in older patients
María Queralt Salas, MD, Hospital Clínic de Barcelona, Barcelona, Spain, briefly discusses the importance of assessing frailty to improve stem cell transplant outcomes in older patients with hematological malignancies, highlighting the use of frailty scales and comprehensive geriatric assessments to better capture patients’ vulnerability and to tailor transplant plans more accurately. This interview took place at the 52nd Annual Meeting of the EBMT in Madrid, Spain.
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Transcript
Well, there is lots of data coming from prospective studies implementing frailty scales or comprehensive geriatric assessments in transplant units for older adults. We can better capture a patient’s vulnerability and gain information about their health status to design transplant more accurately and also help us to better select patients for transplant. In our institution, we use the hematopoietic cell transplant frailty scale, which was designed at Princess Margaret Cancer Center in Toronto, Canada, and it can be done in around 10 minutes by hematologists and nurses...
Well, there is lots of data coming from prospective studies implementing frailty scales or comprehensive geriatric assessments in transplant units for older adults. We can better capture a patient’s vulnerability and gain information about their health status to design transplant more accurately and also help us to better select patients for transplant. In our institution, we use the hematopoietic cell transplant frailty scale, which was designed at Princess Margaret Cancer Center in Toronto, Canada, and it can be done in around 10 minutes by hematologists and nurses. However, there are other scales that are useful also, they can be implemented in other units with team effort, and of course, the comprehensive geriatric assessment will be the best, but you need a specialized team to do these assessments.
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