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Oxford Myeloma Workshop 2025 | The value of multiomics in multiple myeloma research

Aneta Mikulasova, PhD, Newcastle University, Newcastle upon Tyne, UK, briefly discusses the value of multiomics in multiple myeloma (MM) research, highlighting that it can reveal patterns and consequences of genomic abnormalities that are not apparent with single-method approaches. By integrating multiple techniques, researchers can gain a deeper understanding of the underlying disease biology, ultimately leading to the identification of targets for more effective personalized therapies. This interview took place at the 5th Oxford Myeloma Workshop in Oxford, UK.

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Transcript (AI-generated)

If we involve multiomic methods in myeloma research, we can better understand the complete consequences of genomic abnormalities. We know that structural variation is changing gene regulation, but also the regulatory elements, how DNA is organized within the nucleus. And if we apply multiomics, we can find patterns we are not able to see if we use a single method and we often miss...

If we involve multiomic methods in myeloma research, we can better understand the complete consequences of genomic abnormalities. We know that structural variation is changing gene regulation, but also the regulatory elements, how DNA is organized within the nucleus. And if we apply multiomics, we can find patterns we are not able to see if we use a single method and we often miss. So it’s research to go to very basic biology and understanding, but it’s very important steps because if we fully understand what’s happening in the beginning, we can truly find the cause of the disease and where to really target in the future in treatment and developing more effective personalized therapies. 

 

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

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