If we involve multiomic methods in myeloma research, we can better understand the complete consequences of genomic abnormalities. We know that structural variation is changing gene regulation, but also the regulatory elements, how DNA is organized within the nucleus. And if we apply multiomics, we can find patterns we are not able to see if we use a single method and we often miss...
If we involve multiomic methods in myeloma research, we can better understand the complete consequences of genomic abnormalities. We know that structural variation is changing gene regulation, but also the regulatory elements, how DNA is organized within the nucleus. And if we apply multiomics, we can find patterns we are not able to see if we use a single method and we often miss. So it’s research to go to very basic biology and understanding, but it’s very important steps because if we fully understand what’s happening in the beginning, we can truly find the cause of the disease and where to really target in the future in treatment and developing more effective personalized therapies.
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