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Clinical trial updates and time-limited therapy in CLL

In this video, Nitin Jain, MD, University of Texas MD Anderson Cancer Center, Houston, TX, discusses trials being conducted in frontline chronic lymphocytic leukemia (CLL) with time-limited therapy. Dr Jain highlights some of the results from the CLL14 trial (NCT02242942) investigating the use of venetoclax plus obinutuzumab, and briefly mentions the CAPTIVATE trial (NCT02910583), investigating the use of ibrutinib plus venetoclax in CLL. Following this, Dr Jain discusses the benefit of triplet combinations and the need to obtain long-term follow-up data from Phase III trials to choose the best regimens when treating patients. This interview was recorded virtually.