Preetesh Jain, MD, PhD, MD Anderson Cancer Center, Houston, Texas, TX, presents the comprehensive analysis of prognostic factors, outcomes and mutation profiles in patients with mantle cell lymphoma (MCL) with an aggressive histology (blastoid/pleomorphic) or transformed MCL. This interview took place at the 15th International Conference on Malignant Lymphoma (ICML), in Lugano, Switzerland.