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SOHO 2026 | Combining isatuximab, lenalidomide, oral cyclophosphamide, & dexamethasone for HR smoldering myeloma

Maher Salamoon, MD, Al-Baironi Hospital, Damascus, Syria, discusses treating high-risk smoldering multiple myeloma, emphasizing the importance of early diagnosis and treatment to improve progression-free survival. Dr Salamoon presents a study in which a combination of isatuximab, lenalidomide, oral cyclophosphamide, and dexamethasone achieved a high overall response rate and progression-free survival, with manageable side effects. This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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