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SOHO 2026 | Optimizing assessment of treatment resistance and loss of response in CML

Simona Soverini, PhD, University of Bologna, Bologna, Italy, discusses common challenges in assessing treatment resistance and loss of response in chronic myeloid leukemia (CML). She highlights the importance of considering BCR::ABL1 trends, treatment goals, and the individual patient context rather than overinterpreting a single result or narrowly defined treatment milestone, particularly when considering a treatment switch. This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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