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EHA 2026 | Fixed-duration pirtobrutinib plus obinutuzumab shows promise in frontline CLL

Inhye Ahn, MD, Dana-Farber Cancer Institute, Boston, MA, discusses results from a Phase II study (NCT06333262) evaluating fixed-duration pirtobrutinib plus obinutuzumab in previously untreated chronic lymphocytic leukemia (CLL). She reviews the promising response rates, rates of undetectable measurable residual disease (MRD), and favorable cardiovascular safety profile, highlighting the potential of this time-limited combination in the frontline setting. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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