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ASCO 2026 | Expanding patient access to clinical trials after CAR-T failure in R/R LBCL

Dai Chihara, MD, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses factors affecting clinical trial access after CAR-T failure in patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL). Dr Chihara highlights that approximately two-thirds of these patients are ineligible due to severe cytopenias and suggests that the field needs to re-evaluate safe cutoffs for eligibility criteria to ensure timely access to new treatments. This interview took place during the 2026 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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