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ASH 2025 | The risk of Richter’s transformation in the era of targeted therapy

Paul Hampel, MD, Mayo Clinic, Rochester, MN, discusses whether modern targeted therapies change the risk of Richter’s transformation (RT) in chronic lymphocytic leukemia (CLL). He explains that targeted agents do not appear to increase transformation risk compared with chemoimmunotherapy or no treatment at all. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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