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ASH 2025 | A retrospective study of Pola-R-CHP versus R+DA-EPOCH in high-risk DLBCL

Rahul Thakur, MBBS, Roswell Park Comprehensive Cancer Center, Buffalo, NY, shares findings from a retrospective study comparing outcomes with polatuzumab vedotin in combination with rituximab, cyclophosphamide, doxorubicin and prednisone (Pola-R-CHP) versus rituximab and dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (R+DA-EPOCH) in patients with high-risk diffuse large B-cell lymphoma (DLBCL). Dr Thakur reports that outcomes were superior in the Pola-R-CHP arm. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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