ASH 2023 | Regulation of tetraspanin CD63 in CML progression: single-cell analysis of asymmetric HSC division
Ali Turhan
• 9 Dec 2023
Ali Turhan, MD, PhD, University of Paris-Saclay, Paris, France, discusses the findings of a single-cell analysis of genes involved in asymmetric hematopoietic stem cell (HSC) division in chronic myeloid leukemia (CML). During the chronic phase of CML, the tetraspanin CD63 was overexpressed on HSCs. However, during blast crisis in the progression of the disease to acute myeloid leukemia (AML), there was decreased expression of this gene. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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