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ASH 2022 | Ocular AEs observed in patients treated with belantamab mafodotin, lenalidomide & dexamethasone

Evangelos Terpos, MD, PhD, National and Kapodistrian University of Athens, Athens, Greece, highlights the ocular adverse events (AEs) observed in the Phase I/II BelaRd study (NCT04808037), which is investigating the safety and clinical activity of belantamab mafodotin in combination with lenalidomide and dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma (MM). Worsening of cataracts was observed, but no grade 3 or 4 events were recorded. Prof. Terpos also mentions that a questionnaire indicated that most patients experienced a very low frequency of ocular events which affected their daily activity. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

GSK: Honoraria, Research Funding; BMS: Honoraria; EUSA Pharma: Honoraria, Other: Travel expenses; Amgen: Honoraria, Other: Travel expenses, Research Funding; Sanofi: Honoraria, Research Funding; Takeda: Honoraria, Other: Travel expenses, Research Funding; Genesis: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; Novartis: Honoraria.