Jia Ruan, MD, PhD, Weill Cornell Medicine, New York, NY, discusses emerging therapies in mantle cell lymphoma (MCL), drawing focus on the role of immunotherapies. Dr Ruan first highlights the promise of CAR-T cell therapy, and then goes on to comment on the promise of reversible BTK inhibitors, such as pirtobrutinib. Following this, Dr Ruan discusses the potential role of bispecific antibodies in MCL, and further summarizes ongoing clinical trials in this space, as well as the importance of bringing novel agents into earlier lines of therapy. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.
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