Eunice Wang, MD, Roswell Park Comprehensive Cancer Center, Buffalo, NY, outlines approaches to modulate the immune system in myeloid malignancies including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Whilst targeting T-cell immune checkpoint inhibitors (ICIs) such as PD-1 and PD-L1 has not been very successful, targeting other ICIs including CTLA-4, TIM-3, CD47/SIRPα, and manipulating natural killer (NK) cells has led to more promising results. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.