Paolo Caimi, MD, University Hospitals Cleveland Medical Center & Case Western Reserve University, Cleveland, OH, talks on the improving cure rates of non-Hodgkin lymphoma (NHL) and discussess where he sees the field moving in the future. Dr Caimi also outlines novel therapies being developed for NHL treatment, including loncastuximab tesirine, polatuzumab, and selinexor, and comments on the need to target therapies more accurately. This interview took place at the virtual European Hematology Association (EHA) Congress 2021.