Livio Pagano, MD, Catholic University of Sacred Heart, Rome, Italy, discusses challenges associated with using chimeric antigen receptor T-cell (CAR-T) therapy as a bridging therapy to allogeneic stem cell transplantation (allo-SCT), outlining the increased risk of fungal infection. This interview took place during the 47th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT) 2021.