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TCT 2021 | PTCy based GvHD prophylaxis in myelofibrosis

Tania Jain, MBBS, Johns Hopkins University, Baltimore, MD, discusses the results of a retrospective analysis evaluating the outcomes of post-transplantation cyclophosphamide (PTCy) based graft-versus-host disease (GvHD) prophylaxis in patients undergoing allogeneic blood or marrow transplantation for myelofibrosis. Bone marrow transplantation using non-myeloablative conditioning and PTCy for graft-versus-host disease prophylaxis demonstrated comparable clinical outcomes as other studies in myelofibrosis. This interview took place during the Transplantation & Cellular Therapy (TCT) 2021 Meetings.