Thomas Kipps, MD, PhD, from University of California, San Diego, CA, talks to us about ROR1, an embryonic protein involved in the development of chronic lymphocytic leukemia (CLL), and its emerging role in various types of cancer. As elaborated by Dr. Kipps in this interview, cancer patients expressing high levels of ROR1 generally show quicker spreading and metastasis of the disease and this applies to not only CLL, but also in lung, prostate and breast cancers. Understanding the ROR1 survival pathway and its role in CLL is crucial in developing therapy for the disease and knowledge of its role can then be applied to other cancer types. This video was recorded at the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2017 in New York, NY.