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ICML 2023 | The current SOC in CTCL: skin-directed therapy, systemic therapy & clinical challenges

Pierluigi Porcu, MD, Jefferson Health, Sidney Kimmel Cancer Center, Philadelphia, PA, gives an overview of the current standard of care (SOC) in cutaneous T-cell lymphoma (CTCL), which depends on the stage of an individual’s disease. Dr Porcu first discusses various types of skin-directed therapy, and then comments on the challenges of treating patients with early stage disease who fail skin-directed therapies. To conclude, Dr Porcu summarizes various forms of systemic therapy used in CTCL, including retinoids, methotrexate, HDAC inhibitors, and novel immunotherapeutic agents being explored. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.

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