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ISAL 2023 | T-cell bispecifics in AML: ongoing challenges and future outlooks

Marion Subklewe, MD, Ludwig-Maximilians University, Munich, Germany, shares some insights into the current status of T-cell bispecific antibodies in the treatment of acute myeloid leukemia (AML). Prof. Subklewe discusses major challenges with implementing these agents in clinical practice, including the issue of identifying suitable target antigens, overcoming T-cell exhaustion, and the presence of dysfunctional T-cells in AML. This interview took place at the 18th International Symposium on Acute Leukemias (ISAL XVIII), held in Munich, Germany.

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