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ASH 2024 | Chemo-free regimen of inotuzumab + blinatumomab as frontline therapy in older patients with Ph-B-ALL

Jayastu Senapati, MBBS, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on the feasibility of utilizing a chemotherapy-free regimen of inotuzumab ozogamicin plus blinatumomab in older patients with Philadelphia chromosome-negative (Ph-) B-cell acute lymphoblastic leukemia (B-ALL). An ongoing Phase Ib/II trial of this combination in patients over 70 years of age has shown promising results; however, longer-term follow-up data is needed to confirm these. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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